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The signaling pathways related to necroptosis include different mitochondria-related proteins, such as Drp1, AIF, PGAM5, and others
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The expression of CTSK was upregulated in the saline group, while the SP@M treatment effectively suppressed this upregulation (Supplementary Fig
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Lifelong choline supplementation in another Alzheimers disease mouse model (APP/PS1 transgenic mice), significantly diminished amyloid- plaque load and decreased activated microglia, thereby mitigating the detrimental effects of brain inflammation associated with Alzheimers disease (44)
